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Tell your health care provider if you are taking any other medicines, especially any of the following: <ul> <li>Amantadine, antipsychotics (eg, haloperidol, risperidone), corticosteroids (eg, prednisone), insulin, levodopa, MAOIs (eg, phenelzine), nicotine patches, oral hypoglycemics (eg, glipizide), other antidepressants (eg, fluoxetine, amitriptyline), sympathomimetics (eg, pseudoephedrine), theophylline, or tiagabine because they may increase the risk of Wellbutrin ’s side effects</li> <li>Carbamazepine, phenobarbital, or phenytoin because they may decrease Wellbutrin ’s effectiveness</li> <li>Antiarrhythmics (eg, propafenone, flecainide), beta-blockers (eg, metoprolol), phenothiazines (eg, thioridazine), selective serotonin reuptake inhibitor (SSRI) antidepressants (eg, fluoxetine), or tricyclic antidepressants (eg, nortriptyline) because the risk of their side effects may be increased by Wellbutrin</li> </ul> This may not be a complete list of all interactions that may occur. Ask your health care provider if Wellbutrin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. How to use Wellbutrin: Use Wellbutrin as directed by your doctor. Check the label on the medicine for exact dosing instructions. * Wellbutrin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Wellbutrin refilled. * Take Wellbutrin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. * Several weeks may pass before your symptoms improve. Do not stop taking Wellbutrin without checking with your doctor. * Take your doses at the same times each day at least 6 hours apart unless directed otherwise by your doctor. This may help to decrease the risk of seizures with Wellbutrin . * Continue to take Wellbutrin even if you feel well. 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